We develop mechanics-based and data-informed approaches to quantify how soil, groundwater, and environmental and climate-driven loads influence geo-structural performance. Our work targets soil–structure interaction in critical infrastructure, including wind farms, metro systems, harbours, and urban developments. Research spans foundation engineering, underground construction, sloped terrains, and energy storage concepts. We combine field monitoring (terrestrial sensors and Earth Observation/InSAR) with numerical modelling of the geotechnical domain. The outcome is improved prediction of ground–structure response, reduced uncertainty, and decision support through design, construction, and operation.